{"id":4881,"date":"2019-11-12T07:02:20","date_gmt":"2019-11-11T22:02:20","guid":{"rendered":"http:\/\/penqe.com\/riken\/brc_wp3\/?p=4881"},"modified":"2019-11-12T07:02:20","modified_gmt":"2019-11-11T22:02:20","slug":"riken_bioresource_research_center_mouse_mail_news-2","status":"publish","type":"post","link":"http:\/\/web.brc.riken.jp\/en\/archives\/4881","title":{"rendered":"RIKEN BioResource Research Center Mouse Mail News \uff08E-mail ver.\uff09 No. 174 (dummy)"},"content":{"rendered":"************************************************** ******************\nRIKEN BioResource Research Center Mouse Mail News (e-mail version) No. 174\n************************************************** ******************\n\nA fruitful fall. There was news of Dr. Akira Yoshino&#8217;s Nobel Prize in Chemistry.\nI am very happy and proud to have a Japanese Nobel Prize winner this year.\nThe latest information from RIKEN BRC Laboratory Animal Development Office.\n\n\u2501\u2501\u2501\u2501 Next Next \u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\n\u25cf Special feature Mouse of the month\n\u00a0\u00a0&#8220;Mice expressing 3xFLAG-dCas9 useful for analyzing molecular interactions on specific genomic regions&#8221;\n\u25cf Today&#8217;s tool for functional analysis\n\u25cf October 28 (Monday) Announcement of establishment anniversary\n\u25cf Participation report: INFRAFRONTIER satellite workshop at the IMGC 2019\n\u25cf User achievements\n\u25cf Newly deposited mouse strain\n\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\n\n\u250f\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\n\u7279\u96c6 Special Feature Mouse of the Month (October 2019)\n\u2517\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\n\n3xFLAG-dCas9 expressing mice useful for analyzing molecular interactions on specific genomic regions\nRBRC10188 C57BL \/ 6-Gt (ROSA) 26Sor <tm1 (CAG-3XFLAG \/ dCas9, -EGFP) Hfuj>\nRBRC10189 C57BL \/ 6-Gt (ROSA) 26Sor <tm1.1 (CAG-3XFLAG \/ dCas9, -EGFP) Hfuj>\nRBRC10190 C57BL \/ 6-Gt (ROSA) 26Sor <tm1.2 (CAG-3XFLAG \/ dCas9) Hfuj>\nDepositary: Prof. Hotaka Fujii (Graduate School of Medicine, Hirosaki University)\n\nClick here for details\n\u00a0https:\/\/mus.brc.riken.jp\/en\/mouse_of_month\/oct_2019_mm\n\nThis month&#8217;s mouse back number\n\u00a0https:\/\/mus.brc.riken.jp\/en\/mouse_of_month\n\nIf you would like to post on the mouse this month, Laboratory Animal Development Office (animal@brc.riken.jp)\nPlease contact us.\n\n\n\u250f\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\n\u2503 Today&#8217;s tool for functional analysis\n\u2517\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\n\nIntracellular oxidative stress imaging mouse\nRBRC05704 C57BL \/ 6J-Tg (3xARE \/ TK-NRF2 \/ luc) M2Tiw\nRBRC06161 C57BL \/ 6J-Tg (3xARE \/ TK-NRF2 \/ venus) F4Tiw\n\nMice that can conditionally control increased ROS production\nRBRC09859 C57BL \/ 6J-Tg (CMV-cat, -SDHA <*> \/ Y215F) 1Hom\n\nSperm-egg membrane fusion imaging mouse\nRBRC05763 STOCK Izumo1 <tm1Osb> Tg (Clgn-Izumo1 \/ mCherry) Osb Tg (CAG \/ Acr-EGFP) C3-N01-FJ002Osb\n\nSperm acrosome-GFP: sperm mitochondria-DsRed double reporter mouse\nRBRC03743 B6D2-Tg (CAG \/ Su9-DsRed2, Acr3-EGFP) RBGS002Osb\nRBRC05861 B6.Cg-Tg (CAG \/ Su9-DsRed2, Acr3-EGFP) RBGS002Osb\n\nToday&#8217;s tool for functional analysis\n\u00a0https:\/\/mus.brc.riken.jp\/en\/todays_tool_and_model\n\n\n\u250f\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\n28 October 28 (Monday) Announcement of establishment anniversary\n\u2517\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\n\nOctober 28 (Monday) will be closed for the anniversary of establishment.\nWe apologize for the inconvenience and thank you for your understanding.\n\nhttps:\/\/en.brc.riken.jp\/news\/notice_20191015_01.html\n\n\n\u250f\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\n\u5831\u544a Participation report: INFRAFRONTIER satellite workshop at the IMGC 2019\n\u2517\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\n\nParticipation report: INFRAFRONTIER satellite workshop at the IMGC 2019\n\u00a0https:\/\/en.brc.riken.jp\/news\/report_20191008_01.html\n\n\n\u250f\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\n\u6210\u679c User achievements\n\u2517\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\n\nResearch results using mice provided by RIKEN BRC have been announced one after another.\nRIKEN BRC wants to help you discover new things by introducing your achievements\nam thinking. If you have published a paper or obtained a patent, please contact us.\nDoing.\n\nRBRC00445 C57BL \/ 6-Tg (CAG \/ Acr-EGFP) C3-N01-FJ002Osb\nFukunaga H, Kaminaga K, Sato T, Butterworth KT, Watanabe R, Usami N,\nOgawa T, Yokoya A, Prize KM.\nHigh-precision microbeam radiotherapy reveals testicular tissue-sparing\neffects for male fertility preservation.\nSci Rep .; 9 (1): 12618, doi: 10.1038 \/ s41598-019-48772-3, 2019.\nhttps:\/\/doi.org\/10.1038\/s41598-019-48772-3\n\nRBRC00753 B6; 129P2-Sema4d <tm1Kik> \/ Rbrc\nZhang C, Qiao H, Guo W, Liu Y, Yang L, Liu Y, Jin B, Fu M, Wang G, Li W.\nCD100-plexin-B1 induces epithelial-mesenchymal transition of head and neck\nsquamous cell carcinoma and promotes metastasis.\nCancer Lett .; 455: 1-13, doi: 10.1016 \/ j.canlet.2019.04.013, 2019.\nhttps:\/\/doi.org\/10.1016\/j.canlet.2019.04.013\n\nRBRC01834 C57BL \/ 6-Tg (CAG-flpe) 36Ito \/ ItoRbrc\nSakata D, Uruno T, Matsubara K, Andoh T, Yamamura K, Magoshi Y,\nKunimura K, Kamikaseda Y, Furue M, Fukui Y.\nSelective role of neurokinin B in IL-31-induced itch response in mice.\nJ Allergy Clin Immunol .; 144 (4): 1130-1133.e8, doi: 10.1016 \/ j.jaci. 2019.06.031, 2019.\nhttps:\/\/doi.org\/10.1016\/j.jaci.2019.06.031\n\nRBRC05555 B6; B6129-Ezh2 <tm1Yugo> \/ Hko [B6-Ezh2 floxed]\nOhka F, Shinjo K, Deguchi S, Matsui Y, Okuno Y, Katsushima K, Suzuki M,\nKato A, Ogiso N, Yamamichi A, Aoki K, Suzuki H, Sato S, Arul Rayan N,\nPrabhakar S, G\u00f6ke J, Shimamura T, Maruyama R, Takahashi S, Suzumura A,\nKimura H, Wakabayashi T, Zong H, Natsume A, Kondo Y.\nPathogenic Epigenetic Consequences of Genetic Alterations in IDH-wild-type\nDiffuse Astrocytic Gliomas.\nCancer Res .; 79 (19): 4814-4827, doi: 10.1158 \/ 0008-5472. CAN-19-1272, 2019.\nhttps:\/\/doi.org\/10.1158\/0008-5472.CAN-19-1272\n\nRBRC05663 B6.Cg-Bcl6 <tm1.1Mtto>\nOtsuka K, Yamada A, Saito M, Ushio A, Sato M, Kisoda S, Shao W,\nTsunematsu T, Kudo Y, Arakaki R, Ishimaru N.\nAscl2-Regulated Follicular Helper T Cells Promote Autoimmunity\nin a Murine Model for Sj\u00f6gren&#8217;s Syndrome.\nAm J Pathol., Doi: 10.1016 \/ j.ajpath.2019.08.008, 2019.\nhttps:\/\/doi.org\/10.1016\/j.ajpath.2019.08.008\n\nRBRC05704 C57BL \/ 6J-Tg (3xARE \/ TK-NRF2 \/ luc) M2Tiw\nSuzuki T, Muramatsu A, Saito R, Iso T, Shibata T, Kuwata K,\nKawaguchi SI, Iwawaki T, Adachi S, Suda H, Morita M, Uchida K,\nBaird L, Yamamoto M.\nMolecular Mechanism of Cellular Oxidative Stress Sensing by Keap 1.\nCell Rep .; 28 (3): 746-758.e4, doi: 10.1016 \/ j.celrep. 2019.06.047, 2019.\nhttps:\/\/doi.org\/10.1016\/j.celrep.2019.06.047\n\nRBRC06344 C57BL \/ 6-App <tm3 (NL-G-F) Tcs>\nHamaguchi T, Tsutsui-Kimura I, Mimura M, Saito T, Saido TC, Tanaka KF.\nAppNL-G-F \/ NL-G-F mice overall do not show impaired motivation,\nbut cored amyloid plaques in the striatu","protected":false},"excerpt":{"rendered":"************************************************** ****************** RIKEN BioResource Research Center Mouse Mail News (e-mail version) No. 174 ************************************************** ****************** A fruitful fall. There was news of Dr. Akira Yoshino&#8217;s Nobel Prize in Chemistry. I am very happy and proud to have a Japanese Nobel Prize winner this year. The latest information from RIKEN BRC Laboratory Animal Development Office. \u2501\u2501\u2501\u2501 Next Next \u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501 \u25cf Special feature Mouse of the month \u00a0\u00a0&#8220;Mice expressing 3xFLAG-dCas9 useful for analyzing molecular interactions on specific genomic regions&#8221; \u25cf Today&#8217;s tool for functional analysis \u25cf October 28 (Monday) Announcement of establishment anniversary \u25cf Participation report: INFRAFRONTIER satellite workshop at the IMGC 2019 \u25cf User achievements \u25cf Newly deposited mouse strain \u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501\u2501 &hellip; <p class=\"link-more\"><a href=\"http:\/\/web.brc.riken.jp\/en\/archives\/4881\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;RIKEN BioResource Research Center Mouse Mail News \uff08E-mail ver.\uff09 No. 174 (dummy)&#8221;<\/span><\/a><\/p>","protected":false},"author":12,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_seopress_robots_primary_cat":"","_seopress_titles_title":"","_seopress_titles_desc":"","_seopress_robots_index":"","footnotes":"","_wp_rev_ctl_limit":""},"categories":[12],"tags":[],"class_list":["post-4881","post","type-post","status-publish","format-standard","hentry","category-mus-announce","entry"],"acf":[],"_links":{"self":[{"href":"http:\/\/web.brc.riken.jp\/en\/wp-json\/wp\/v2\/posts\/4881","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/web.brc.riken.jp\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/web.brc.riken.jp\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/web.brc.riken.jp\/en\/wp-json\/wp\/v2\/users\/12"}],"replies":[{"embeddable":true,"href":"http:\/\/web.brc.riken.jp\/en\/wp-json\/wp\/v2\/comments?post=4881"}],"version-history":[{"count":0,"href":"http:\/\/web.brc.riken.jp\/en\/wp-json\/wp\/v2\/posts\/4881\/revisions"}],"wp:attachment":[{"href":"http:\/\/web.brc.riken.jp\/en\/wp-json\/wp\/v2\/media?parent=4881"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/web.brc.riken.jp\/en\/wp-json\/wp\/v2\/categories?post=4881"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/web.brc.riken.jp\/en\/wp-json\/wp\/v2\/tags?post=4881"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}